The proteome of clear cell ovarian carcinoma

Author: rkbj

August undefined, 2024

Webb1 okt. 2024 · Clear cell borderline ovarian tumor (CCBOT) is one of the rarest subtypes of borderline ovarian malignancies. The aim of this study was to determine the prognosis of a series of CCBOT. Patients and Methods A retrospective review of patients with CCBOT treated or referred to our institutions. Webbthe primary effect on the proteome of arid1a-mutated ovarian clear cell carcinoma is downregulation of the mevalonate pathway at the post-transcriptional level running title: …

Clear cell carcinoma of the ovary: a clinical and molecular …

WebbRenal Cell Carcinoma (RCC) comprises a heterogeneous group of tumors of which the most frequent (70–80%) and aggressive morphotype is clear cell RCC (ccRCC) [1,2].In … WebbWhen administered in combination to A2780 and A2780/CP ovarian cancer cells, the two drugs inhibited ovarian cancer cell growth additively/synergistically. Together, these results support the idea that X-ray crystallography can provide structural indicators for designing combinations of hTS (or any other target)-directed drugs to accelerate preclinical … fmf services

Proteomic signatures of clear cell renal cell carcinoma

Webb5 juli 2024 · Clear cell carcinoma of the ovary represents 5% to 25% of all epithelial ovarian cancers, depending on geographic location 2. Substantial ethnic and/or racial differences in the distribution of different histological types of … Webb18 sep. 2024 · Clear cell carcinoma has a higher frequency of telomerase reverse transcriptase ( TERT) promoter mutation (5.7%–16.0%) than other histological types of … Webb11 juni 2024 · Patients with clear cell ovarian carcinoma have high recurrence rates, even in early-stage disease and when complete resection is achieved, according to a new analysis of a randomized phase III trial comparing paclitaxel plus carboplatin vs irinotecan plus cisplatin in this setting. fmf service waldaschaff

The Primary Effect on the Proteome of ARID1A-mutated Ovarian …

Webb20 nov. 2000 · Clear cell carcinoma of the ovary (CCC) originally was termed mesonephroid by Schiller in 1939 because it was believed to originate from mesonephric … Webb1 juni 2012 · On the other hand, ovarian tumor with rare histologic subtypes such as clear cell or mucinous tumors have been recognized to show chemo-resistant phenotype, … fmf shorty logo black and whiteWebbClear cell carcinoma of the ovary is a rare and distinct histotype of epithelial ovarian carcinomas. Women diagnosed with clear cell carcinomas are usually younger and … fmfs inc

"Webb8 dec. 2024 · Background Patients with ovarian clear cell carcinoma (OCCC) have a poor prognosis because they show low sensitivity to platinum-based chemotherapy. New treatments for refractory OCCC are urgently needed. Case presentation We present a patient with refractory OCCC in whom conventional chemotherapy failed. Cachexia was … " - The proteome of clear cell ovarian carcinoma

The proteome of clear cell ovarian carcinoma

IJMS Free Full-Text Ovarian Cancer: Can Proteomics Give New ...

Webb14 okt. 2024 · Clear cell ovarian carcinoma (CCOC) is the second most common subtype of epithelial ovarian carcinoma. Late-stage CCOC is not responsive to gold-standard chemotherapy and results in suboptimal outcomes for patients. In-depth molecular insight is urgently needed to stratify the disease and drive therapeutic development. Webb31 okt. 2016 · There is currently no reliable serum biomarker for ovarian clear cell carcinoma (CCC), a highly lethal histological subtype of epithelial ovarian cancer (EOC). Previously, using a proteome-based approach, we identified tissue factor pathway inhibitor 2 (TFPI2) as a candidate serum biomarker for CCC.

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WebbA substantial proportion of Acanthopagrus schlegelii individuals change sex from male to female during their lifetime. However, the mechanisms underlying sex change are unknown. In this research, iTRAQ analyses of proteins obtained from A.schlegelii gonads in four different stages of development were compared. In total, 4692 proteins were …

Webb7 mars 2014 · Epithelial ovarian cancer (EOC) is often asymptomatic and thus diagnosed at advanced stages with a poor prognosis. False-negative results for the conventional … Webb15 apr. 2013 · Ovarian cancer represents one of the four main gynecological cancers, counting worldwide about 225,000 new cancer cases diagnosed in 2008 (3.7% of all female cancers) and about 140,000 deaths (4.2% of all deaths in women) [ 1 ]. According to the American Cancer Society, in 2012, ovarian cancer was expected to account for 3% …

WebbClear cell ovarian carcinoma (CCOC) is the second most common subtype of epithelial ovarian carcinoma. Late-stage CCOC is not responsive to gold-standard chemotherapy and results in suboptimal outcomes for patients. In-depth molecular insight is urgently … Webb23 aug. 2024 · Oxyphilic variant of clear cell carcinoma is composed of tumor cells with variable amounts of clear to granular eosinophilic cytoplasm (oxyphil cells), especially in nested, solid or trabecular growths ( Am J Surg Pathol 1987;11:661 ) Rare features: Multinucleated cells Psammoma bodies

Webb5 juli 2016 · Ovarian clear cell carcinomas (OCCC) comprise between 5 and 25% of all epithelial ovarian cancers and are often associated with endometriosis ( 1 ). Patients with advanced OCCC generally respond poorly to standard platinum-based chemotherapy and have a median 5-year survival rate of less than 32% ( 2, 3 ).

WebbOvarian Cancer Proteomics of FFPE Tissue Description We have performed in-depth examination of single tissue sections from a collection of FFPE and Frozen treated tumors, as well as cell line material all originating from different subtypes of epithelial ovarian cancer (high-grade serous, clear cell, endometrioid). greensburg in courthouseWebb26 aug. 2016 · A cell line representative of human high-grade serous ovarian cancer (HGSOC) should not only resemble its tumour of origin at the molecular level, but also demonstrate functional utility in pre ... greensburg indiana 47240 weatherWebbKnockout of ARID1A in an ovarian clear cell carcinoma cell line with wild-type ARID1A, OVCA429, primarily resulted in downregulation of the mevalonate pathway, an important … fmf shorty packingWebbMolecular stratification of high-grade serous ovarian carcinoma (HGSC) for targeted therapy is a pertinent approach in improving prognosis of this highly heterogeneous … greensburg indiana american rentalWebb28 aug. 2024 · The proteome of clear cell ovarian carcinoma. Jennifer X Ji Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada. … greensburg indiana animal shelterWebb10 rader · 28 aug. 2024 · Clear cell ovarian carcinoma (CCOC) is the second most common subtype of epithelial ... fmf sncWebb5 nov. 2024 · Ovarian carcinoma reflects the biggest challenge among the field of gynecologic oncology. It represents the most common death cause of genital … fmf shorty logo